Preface ------- The Joint European and National Astronomical Meeting (JENAM99) of the European Astronomical Society and the French Astronomical Society was held in Toulouse in September 1999. Nearly four hundred participants gathered during one week to attend nine plenary conferences opening each day and to subsequently work in a total of ten parallel sessions on a variety of topics covering star formation, asteroseismology, dynamics of star clusters, massive stars and the ISM, active galactic nuclei, astrophysical fluid dynamics, cosmic microwave background anisotropies, neutrinos in astrophysics, very high energy and gravitational wave astrophysics. The present volume constitutes the proceedings of the two day session on "The Interplay between Massive Stars and the ISM". The aim of this session was to gather specialists from different fields which allow to contribute to a consistent picture of the phenomena governing the multiple and complex interactions between these two important constituents of galaxies. The main topics addressed were: the stellar content and physics of massive star-forming regions, chemical enrichment by massive stars, and the dynamical impact of star formation on the ISM. The session was very well attended both by participants fully "dedicated" to this subject as well as "interacting" visitors from other parallel sessions, resulting in both lively and fruitful presentations and discussions. Thanks to all participants who contributed to this success. We are grateful for the help received from the Scientific Organising Committee (SOC) of our session which consisted of Federico Ferrini (Pisa), Rosa Gonzalez-Delgado (Granada, co-chair), Mohammad Heydari-Malayeri (Paris), Dieter Lutz (Munich), Andre Maeder (Switzerland), Daniel Schaerer (Toulouse, co-chair) and Roberto Terlevich (Cambridge). We would also like to thank Livia Origlia, Cesar Esteban and Nikos Prantzos for the work as chairpersons. Last but not least the JENAM99 SOC and the local organisers, chaired by Sylvie Vauclair, are thanked for all their work. These proceedings have been possible through partial support from the JENAM99 LOC and an INTAS grant to DS. Daniel Schaerer and Rosa Gonzalez Delgado Toulouse and Granada, january 2000